Many people with keratoconus also have allergies, and eye doctors have long suspected that itching and rubbing play a role. A large study published in the American Journal of Ophthalmology in September 2026, led by researchers at the University of Toronto, looked at that link in a big, diverse group of Americans.
What the researchers did
The team used the National Institutes of Health’s All of Us Research Program. They scored each person from 0 to 3 based on how many of three allergic (“atopic”) conditions they had: asthma, eczema (atopic dermatitis) and hay fever (allergic rhinitis).
- A long-term group of 283,040 adults without keratoconus was followed for a median of 9 years; 498 developed keratoconus.
- A second snapshot group included 508,527 adults, 741 of whom had keratoconus.
What they found
- Each added allergic condition raised the risk of a new keratoconus diagnosis by about 59%.
- Among people aged 18 to 40, the link was stronger, about 74% per condition, and new cases were diagnosed at a median age of 38.
- Allergic conjunctivitis (itchy eye allergy) on its own was linked to nearly three times the odds of keratoconus.
- In most people with both, the allergy diagnosis came first.
The authors were careful to note a limitation: people who see doctors more often are more likely to be diagnosed with everything. When they matched patients for how often they used health care, the link weakened, although that analysis was small and could not rule out a real effect.
What this means for you
- If you have asthma, eczema or hay fever and notice blurry or changing vision, ask for a corneal shape scan (topography), not only a new glasses prescription.
- Treat itchy eyes. Cold compresses and allergy drops recommended by your eye doctor can reduce the urge to rub.
- Do not rub your eyes, especially with knuckles. Pat or press gently with a cool cloth instead.
- Family members of people with keratoconus should have their corneas checked.
For reliable explanations of retinal conditions that can also blur vision, see this retina education site.
In my keratoconus patients, controlling allergy and stopping eye rubbing is one of the first things we work on together.
Source: Cumulative Atopic Disease Burden and Keratoconus: Cross-Sectional and Longitudinal Associations in the All of Us Research Program (American Journal of Ophthalmology (PubMed), 09/06/2026). This article is an educational summary written by Khanna Vision Institute and is not a substitute for medical advice.